Also available as Remedy's Nutrition® Passionflower Capsules
Learn all about Remedy's Nutrition® Passionflower Tincture
Passionflower is a medicinal plant used for its calming and soothing effects. It contains compounds that lower brain activity, which may help you relax and improve...
Show more...Also available as Remedy's Nutrition® Passionflower Capsules
Learn all about Remedy's Nutrition® Passionflower Tincture
Passionflower is a medicinal plant used for its calming and soothing effects. It contains compounds that lower brain activity, which may help you relax and improve your sleep quality.
Passionflower plant is commonly used to alleviate stomach problems, reduce stress and anxiety, calm the mind, and aid sleep.
Remedy's Nutrition® Passionflower Tincture is powerful, potent, and affordable, all with the highest quality ingredients!
Remedy's Nutrition® Passionflower Tincture may assist with:
Calm mind
Better sleep
Reduce pain
Stress and anxiety
Stomach problems
Passionflower (Passiflora incarnata) is a fast-growing perennial vine with climbing or trailing stems from the Passifloraceae family. It's native to the United States, and it's also known as Maypop, Purple Passionflower, True Passionflower, Wild Apricot, Wild Passion Vine.
Research
History of Passionflower
Familiar Name:
Maypop, Purple Passionflower, True Passionflower, Wild Apricot, Wild Passion Vine
Scientific Name:
Passiflora incarnata
Order:
Malpighiales
Parts Used in Supplement:
Root
Grown In:
The United States
For centuries, Passionflower has been used as a mild sedative by people around the world. Besides, Native Americans used Passionflower to treat boils, wounds, earaches, liver problems, and much more.
Studies and Trials for Passionflower
"A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality."
The aim of the present study was to investigate the efficacy of Passiflora incarnata herbal tea on human sleep, as measured using sleep diaries validated by polysomnography (PSG).
This study featured a double-blind, placebo-controlled, repeated-measures design with a counterbalanced order of treatments (Passionflower vs placebo tea), separated by a 1 week 'washout' period. Forty-one participants (18-35 years) were exposed to each treatment for a week, whereby they consumed a cup of the tea and filled out a sleep diary for 7 days, and completed Spielberger's state-trait anxiety inventory on the seventh morning. Ten participants also underwent overnight PSG on the last night of each treatment period. Of six sleep-diary measures analysed, sleep quality showed a significantly better rating for passionflower compared with placebo (t(40) = 2.70, p < 0.01).
The results of this trial suggest that the consumption of a low dose of Passiflora incarnata yields short-term subjective sleep benefits for healthy adults with mild fluctuations in sleep quality.
Ngan A, Conduit R. A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (Passionflower) herbal tea on subjective sleep quality. Phytother Res. 2011 Aug;25(8):1153-9. doi: 10.1002/ptr.3400. Epub 2011 Feb 3. PMID: 21294203.
Difference
Remedy's Nutrition® Passionflower Tincture features:
100% Pure, High-Quality Herbal Tincture
1:2 Alcohol to Herb Ratio
Longest Steeping Process (up to 3 months)
Hand Strained Purity
Glass Bottle & Dropper
Approved By Herbalist & Pharmacist
Quality Supplements Since 1972
Herbalist, Pharmacist, and Practioner Approved
No Fillers, Additives, Dairy, Corn, Gluten, Preservatives
Vegan, Non-GMO, Kosher & Keto
Formula based on 7 Clinical Studies
Amazing Quality at Super Reasonable Pricing
Independent 3rd Party Testing
100% Risk-Free, Satisfaction Guarantee
When you buy supplements from Remedy's Nutrition®, you get the absolute best available. The best quality, the most beneficial products available anywhere, guaranteed!
Remedy™s® Means Results! Quality, Purity, Pride.
Dosage
Dosage - How much Remedy's Nutrition® Passionflower should I take?
Remedy's Nutrition® Passionflower can be taken with a meal in the morning/evening. We do not add binders, fillers, or additives to our herbal supplements. Our supplements are easily digestible, and the absorption is greatly improved over other inferior herbal supplements.
2ml (40 drops)
Take as needed.
May be taken with a meal in the morning/evening.
Feel free to contact us for a recommendation on how to take this supplement.
Cautions
Cautions
Potential Side Effects
Possible side effects may include sleepiness, dizziness, confusion, nausea, vomiting, rapid heart rhythm, and loss of coordination.
Drug interactions
Passionflower may interact with certain medications. Consult your physician for potential drug interactions before taking Passionflower.
Pregnancy and breast-feeding
Do not use Passionflower during pregnancy and breastfeeding. Consult your physician before using Passionflower.
Surgery
Consult your physician if you are scheduled for a surgery.
Other Cautions
Passionflower has sedative effects. Do not combine it with alcoholic beverages or prescription sedatives.
Always consult with a healthcare practitioner before taking any new supplement.
Often Taken With
Remedy's Nutrition® Passionflower is often taken with these:
Remedy's Nutrition® Stress Management Power Pack
Remedy's Nutrition® Sleep Power Pack
Remedy's Nutrition® Adrenal Support [Stress, Metabolism, Fatigue]
Remedy's Nutrition® Happy Surfer Capsules
Remedy's Nutrition® Pain Master
Remedy's Nutrition® Mega Sleep
Remedy's Nutrition® Full Spectrum CBD Oil
Q & A
Q & A about Remedy's Nutrition® Passionflower
What is Passionflower?
Passionflower (Passiflora incarnata) is a fast-growing perennial vine with climbing or trailing stems from the Passifloraceae family. It's native to the United States, and it's also known as Maypop, Purple Passionflower, True Passionflower, Wild Apricot, Wild Passion Vine.
What is Passionflower good for?
The passionflower plant is commonly used to alleviate stomach problems, reduce stress and anxiety, calm the mind, and aid sleep.
Can I use Passionflower every day?
Yes, 2ml (40 drops) may be taken with a meal in the morning/evening, or as instructed by your healthcare provider.
Are there any side effects of taking Passionflower?
Possible side effects may include sleepiness, dizziness, confusion, nausea, vomiting, rapid heart rhythm, and coordination loss. Always consult with a healthcare practitioner before taking any new supplement.
Does Passionflower interact with any medications?
Passionflower has sedative effects. Do not combine it with alcoholic beverages or prescription sedatives. And consult your physician for other potential drug interactions before taking it.
Is Passionflower supplement safe for kids?
Ensure you keep the Passionflower supplement out of reach of children and consult your physician before using it with children.
Can I use a Passionflower supplement during pregnancy or while breastfeeding?
Do not use Passionflower during pregnancy and breastfeeding. Consult your physician before using Passionflower.
How is Remedy's Nutrition® Passionflower Tincture prepared?
Each ingredient comes to our on-site location in raw form, each product is then blended, according to a proprietary formula.
Do you sell Passionflower in another form?
Yes, we also have available Remedy's Nutrition® Passionflower Capsules.
Can Remedy's Nutrition® Passionflower cure my health condition?
We do not promote Remedy's Nutrition® Passionflower Tincture to diagnose, treat, cure, or prevent disease.
Why choose Remedy's Nutrition® Passionflower supplement?
Remedy's Nutrition® Passionflower supplement is 100% pure and high-quality Passiflora incarnata herb. It's pharmacist reviewed and approved and free of fillers, additives, and preservatives. Quality and potency are guaranteed!
ieve passionflower works by increasing levels of a chemical called gamma aminobutyric acid (GABA) in the brain. GABA lowers the activity of some brain cells.
The effects of passionflower tend to be milder than valerian (Valeriana officinalis) or kava (Piper methysticum). Passionflower is often combined with valerian, lemon balm (Melissa officinalis), or other herbs. Few scientific studies have tested passionflower as a treatment option, however, and since passionflower is often combined with other herbs, it is difficult to tell what effects passionflower has on its own.
Plant Description
Native to southeastern parts of the Americas, passionflower is now grown throughout Europe. It is a perennial climbing vine with herbaceous shoots and a sturdy woody stem that grows to a length of nearly 10 meters (about 32 feet). Each flower has 5 white petals and 5 sepals that vary in color from magenta to blue. According to folklore, passionflower got its name because its corona resembles the crown of thorns worn by Jesus during the crucifixion. The passionflower's ripe fruit is an egg-shaped berry that may be yellow or purple. Some kinds of passionfruit are edible.
Parts Used
The above ground parts (flowers, leaves, and stems) of the passionflower are used for medicinal purposes.
Available Forms
Available forms include the following:
Infusions
Teas
Liquid extracts
Tinctures
How to Take It
Pediatric
No studies have examined the effects of passionflower in children, so do not give passionflower to a child without a doctor's supervision. Adjust the recommended adult dose to account for the child's weight.
Adult
The following are examples of forms and doses used for adults. Speak to your doctor for specific recommendations for your condition:
Tea: Steep 0.5 - 2 g (about 1 tsp.) of dried herb in 1 cup boiling water for 10 minutes; strain and cool. For anxiety, drink 3 - 4 cups per day. For insomnia, drink one cup an hour before going to bed.
Fluid extract (1:1 in 25% alcohol): 10 - 20 drops, 3 times a day
Tincture (1:5 in 45% alcohol): 10 - 45 drops, 3 times a day
Precautions
The use of herbs is a time honored approach to strengthening the body and treating disease. Herbs, however, can trigger side effects and can interact with other herbs, supplements, or medications. For these reasons, you should take herbs with care, under the supervision of a health care provider.
Do not take passionflower if you are pregnant or breastfeeding.
For others, passionflower is generally considered to be safe and nontoxic in recommended doses.
Possible Interactions
Passionflower may interact with the following medications:
Sedatives (drugs that cause sleepiness) -- Because of its calming effect, passionflower may make the effects of sedative medications stronger. These medications include:
Anticonvulsants such as phenytoin (Dilantin)
Barbiturates
Benzodiazepines such as alprazolam (Xanax) and diazepam (Valium)
Drugs for insomnia, such as zolpidem (Ambien), zaleplon (Sonata), eszopiclone (Lunesta), ramelteon (Rozerem)
Tricyclic antidepressants, such as amitriptyline (Elavil), amoxapine, doxepin (Sinequan), and nortriptyline (Pamelor)
Antiplatelets and anticoagulants (blood thinners) -- Passionflower may increase the amount of time blood needs to clot, so it could make the effects of blood thinning medications stronger and increase your risk of bleeding. Blood thinning drugs include:
Clopidogrel (Plavix)
Warfarin (Coumadin)
Aspirin
Monoamine oxidase inhibitors (MAO inhibitors or MAOIs) -- MAO inhibitors are an older class of antidepressants that are not often prescribed now. Theoretically, passionflower might increase the effects of MAO inhibitors, as well as their side effects, which can be dangerous. These drugs include:
Isocarboxazid (Marplan)
Phenelzine (Nardil)
Tranylcypromine (Parnate)
Supporting Research
Akhondzadeh S, Naghavi HR, Vazirian M, Shayeganpour A, Rashidi H, Khani M. Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam. J Clin Pharm Ther. 2001;26(5):369-373.
Akhondzadeh S. Passionflower in the treatment of opiates withdrawal: a double-blind randomized controlled trial. J Clin Pharm Ther. 2001;26(5):369-373.
Barbosa PR, Valvassori SS, Bordignon CL Jr, Kappel VD, Martins MR, Gavioli EC, et al. The aqueous extracts of Passiflora alata and Passiflora edulis reduce anxiety-related behaviors without affecting memory process in rats. J Med Food. 2008 Jun;11(2):282-8.
Blumenthal M, Goldberg A, Brinckmann J. Herbal Medicine: Expanded Commission E Monographs. Newton, MA: Integrative Medicine Communications; 2000:293-296.
Dhawan K, Kumar S, Sharma A. Anxiolytic activity of aerial and underground parts of Passifloraincarnata. Fitoterapia. 2001;72:922-6.
Dhawan K, Kumar S, Sharma A. Anti-anxiety studies on extracts of Passiflora incarnata Linneaus. J Ethnopharmacol. 2001;78:165-70.
Elsas SM, Rossi DJ, Raber J, White G, Seeley CA, Gregory WL, Mohr C, Pfankuch T, Soumyanath A. Passionflora incarnata L. (Passionflower) extracts elicit GABA currents in hippocampal neurons in vitro, and show anxiogenic and anticonvulsant effects in vivo, varying with extraction method. Phytomedicine. 2010;17(12):940-9.
Ernst E, ed. Passionflower. The Desktop Guide to Complementary and Alternative Medicine. Edinburgh: Mosby; 2001:140-141.
Grundmann O, Wang J, McGregor GP, Butterweck V. Anxiolytic Activity of a Phytochemically Characterized Passiflora incarnata Extract is Mediated via the GABAergic System. Planta Med. 2008 Dec;74(15):1769-73.
Lakhan SE, Vieira KF. Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review. Nutr J. 2010;9:42.
Larzelere MM, Wiseman P. Anxiety, depression, and insomnia. Prim Care. 2002 Jun;29(2):339-60, vii. Review.
Miyasaka L, Atallah A, Soares B. Passiflora for anxiety disorder. Cochrane Database Syst Rev. 2007 Jan 24;(1):CD004518.
Movafegh A, Alizadeh R, Hajimohamadi F, Esfehani F, Nejatfar M. Preoperative oral Passiflora incarnata reduces anxiety in ambulatory surgery patients: a double-blind, placebo-controlled study. Anesth Analg. 2008 Jun;106(6):1728-32.
Rotblatt M, Ziment I. Evidence-Based Herbal Medicine. Philadelphia, PA: Hanley & Belfus, Inc; 2002;294-297.
Sarris J. Herbal medicines in the treatment of psychiatric disorders: a systematic review. Phytother Res. 2007 Aug;21(8):703-16. Review.
Soulimani R, Younos C, Jarmouni S, Bousta D, Misslin R, Mortier F. Behavioural effects of
Watson RR, Zibadi S, Rafatpanah H, Jabbari F, Ghasemi R, Ghafari J, et al. Oral administration of the purple passion fruit peel extract reduces wheeze and cough and improves shortness of breath in adults with asthma. Nutr Res. 2008 Mar;28(3):166-71.
Alternative Names
Passiflora incarnata; Maypop
Version Info
Last Reviewed on 06/23/2011
Steven D. Ehrlich, NMD, Solutions Acupuncture, a private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
Learn all about Remedy's Nutrition® Passionflower Tincture
Passionflower is a medicinal plant used for its calming and soothing effects. It contains compounds that lower brain activity, which may help you relax and improve...
Show more...Also available as Remedy's Nutrition® Passionflower Capsules
Learn all about Remedy's Nutrition® Passionflower Tincture
Passionflower is a medicinal plant used for its calming and soothing effects. It contains compounds that lower brain activity, which may help you relax and improve your sleep quality.
Passionflower plant is commonly used to alleviate stomach problems, reduce stress and anxiety, calm the mind, and aid sleep.
Remedy's Nutrition® Passionflower Tincture is powerful, potent, and affordable, all with the highest quality ingredients!
Remedy's Nutrition® Passionflower Tincture may assist with:
Calm mind
Better sleep
Reduce pain
Stress and anxiety
Stomach problems
Passionflower (Passiflora incarnata) is a fast-growing perennial vine with climbing or trailing stems from the Passifloraceae family. It's native to the United States, and it's also known as Maypop, Purple Passionflower, True Passionflower, Wild Apricot, Wild Passion Vine.
Research
History of Passionflower
Familiar Name:
Maypop, Purple Passionflower, True Passionflower, Wild Apricot, Wild Passion Vine
Scientific Name:
Passiflora incarnata
Order:
Malpighiales
Parts Used in Supplement:
Root
Grown In:
The United States
For centuries, Passionflower has been used as a mild sedative by people around the world. Besides, Native Americans used Passionflower to treat boils, wounds, earaches, liver problems, and much more.
Studies and Trials for Passionflower
"A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality."
The aim of the present study was to investigate the efficacy of Passiflora incarnata herbal tea on human sleep, as measured using sleep diaries validated by polysomnography (PSG).
This study featured a double-blind, placebo-controlled, repeated-measures design with a counterbalanced order of treatments (Passionflower vs placebo tea), separated by a 1 week 'washout' period. Forty-one participants (18-35 years) were exposed to each treatment for a week, whereby they consumed a cup of the tea and filled out a sleep diary for 7 days, and completed Spielberger's state-trait anxiety inventory on the seventh morning. Ten participants also underwent overnight PSG on the last night of each treatment period. Of six sleep-diary measures analysed, sleep quality showed a significantly better rating for passionflower compared with placebo (t(40) = 2.70, p < 0.01).
The results of this trial suggest that the consumption of a low dose of Passiflora incarnata yields short-term subjective sleep benefits for healthy adults with mild fluctuations in sleep quality.
Ngan A, Conduit R. A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (Passionflower) herbal tea on subjective sleep quality. Phytother Res. 2011 Aug;25(8):1153-9. doi: 10.1002/ptr.3400. Epub 2011 Feb 3. PMID: 21294203.
Difference
Remedy's Nutrition® Passionflower Tincture features:
100% Pure, High-Quality Herbal Tincture
1:2 Alcohol to Herb Ratio
Longest Steeping Process (up to 3 months)
Hand Strained Purity
Glass Bottle & Dropper
Approved By Herbalist & Pharmacist
Quality Supplements Since 1972
Herbalist, Pharmacist, and Practioner Approved
No Fillers, Additives, Dairy, Corn, Gluten, Preservatives
Vegan, Non-GMO, Kosher & Keto
Formula based on 7 Clinical Studies
Amazing Quality at Super Reasonable Pricing
Independent 3rd Party Testing
100% Risk-Free, Satisfaction Guarantee
When you buy supplements from Remedy's Nutrition®, you get the absolute best available. The best quality, the most beneficial products available anywhere, guaranteed!
Remedy™s® Means Results! Quality, Purity, Pride.
Dosage
Dosage - How much Remedy's Nutrition® Passionflower should I take?
Remedy's Nutrition® Passionflower can be taken with a meal in the morning/evening. We do not add binders, fillers, or additives to our herbal supplements. Our supplements are easily digestible, and the absorption is greatly improved over other inferior herbal supplements.
2ml (40 drops)
Take as needed.
May be taken with a meal in the morning/evening.
Feel free to contact us for a recommendation on how to take this supplement.
Cautions
Cautions
Potential Side Effects
Possible side effects may include sleepiness, dizziness, confusion, nausea, vomiting, rapid heart rhythm, and loss of coordination.
Drug interactions
Passionflower may interact with certain medications. Consult your physician for potential drug interactions before taking Passionflower.
Pregnancy and breast-feeding
Do not use Passionflower during pregnancy and breastfeeding. Consult your physician before using Passionflower.
Surgery
Consult your physician if you are scheduled for a surgery.
Other Cautions
Passionflower has sedative effects. Do not combine it with alcoholic beverages or prescription sedatives.
Always consult with a healthcare practitioner before taking any new supplement.
Often Taken With
Remedy's Nutrition® Passionflower is often taken with these:
Remedy's Nutrition® Stress Management Power Pack
Remedy's Nutrition® Sleep Power Pack
Remedy's Nutrition® Adrenal Support [Stress, Metabolism, Fatigue]
Remedy's Nutrition® Happy Surfer Capsules
Remedy's Nutrition® Pain Master
Remedy's Nutrition® Mega Sleep
Remedy's Nutrition® Full Spectrum CBD Oil
Q & A
Q & A about Remedy's Nutrition® Passionflower
What is Passionflower?
Passionflower (Passiflora incarnata) is a fast-growing perennial vine with climbing or trailing stems from the Passifloraceae family. It's native to the United States, and it's also known as Maypop, Purple Passionflower, True Passionflower, Wild Apricot, Wild Passion Vine.
What is Passionflower good for?
The passionflower plant is commonly used to alleviate stomach problems, reduce stress and anxiety, calm the mind, and aid sleep.
Can I use Passionflower every day?
Yes, 2ml (40 drops) may be taken with a meal in the morning/evening, or as instructed by your healthcare provider.
Are there any side effects of taking Passionflower?
Possible side effects may include sleepiness, dizziness, confusion, nausea, vomiting, rapid heart rhythm, and coordination loss. Always consult with a healthcare practitioner before taking any new supplement.
Does Passionflower interact with any medications?
Passionflower has sedative effects. Do not combine it with alcoholic beverages or prescription sedatives. And consult your physician for other potential drug interactions before taking it.
Is Passionflower supplement safe for kids?
Ensure you keep the Passionflower supplement out of reach of children and consult your physician before using it with children.
Can I use a Passionflower supplement during pregnancy or while breastfeeding?
Do not use Passionflower during pregnancy and breastfeeding. Consult your physician before using Passionflower.
How is Remedy's Nutrition® Passionflower Tincture prepared?
Each ingredient comes to our on-site location in raw form, each product is then blended, according to a proprietary formula.
Do you sell Passionflower in another form?
Yes, we also have available Remedy's Nutrition® Passionflower Capsules.
Can Remedy's Nutrition® Passionflower cure my health condition?
We do not promote Remedy's Nutrition® Passionflower Tincture to diagnose, treat, cure, or prevent disease.
Why choose Remedy's Nutrition® Passionflower supplement?
Remedy's Nutrition® Passionflower supplement is 100% pure and high-quality Passiflora incarnata herb. It's pharmacist reviewed and approved and free of fillers, additives, and preservatives. Quality and potency are guaranteed!
ieve passionflower works by increasing levels of a chemical called gamma aminobutyric acid (GABA) in the brain. GABA lowers the activity of some brain cells.
The effects of passionflower tend to be milder than valerian (Valeriana officinalis) or kava (Piper methysticum). Passionflower is often combined with valerian, lemon balm (Melissa officinalis), or other herbs. Few scientific studies have tested passionflower as a treatment option, however, and since passionflower is often combined with other herbs, it is difficult to tell what effects passionflower has on its own.
Plant Description
Native to southeastern parts of the Americas, passionflower is now grown throughout Europe. It is a perennial climbing vine with herbaceous shoots and a sturdy woody stem that grows to a length of nearly 10 meters (about 32 feet). Each flower has 5 white petals and 5 sepals that vary in color from magenta to blue. According to folklore, passionflower got its name because its corona resembles the crown of thorns worn by Jesus during the crucifixion. The passionflower's ripe fruit is an egg-shaped berry that may be yellow or purple. Some kinds of passionfruit are edible.
Parts Used
The above ground parts (flowers, leaves, and stems) of the passionflower are used for medicinal purposes.
Available Forms
Available forms include the following:
Infusions
Teas
Liquid extracts
Tinctures
How to Take It
Pediatric
No studies have examined the effects of passionflower in children, so do not give passionflower to a child without a doctor's supervision. Adjust the recommended adult dose to account for the child's weight.
Adult
The following are examples of forms and doses used for adults. Speak to your doctor for specific recommendations for your condition:
Tea: Steep 0.5 - 2 g (about 1 tsp.) of dried herb in 1 cup boiling water for 10 minutes; strain and cool. For anxiety, drink 3 - 4 cups per day. For insomnia, drink one cup an hour before going to bed.
Fluid extract (1:1 in 25% alcohol): 10 - 20 drops, 3 times a day
Tincture (1:5 in 45% alcohol): 10 - 45 drops, 3 times a day
Precautions
The use of herbs is a time honored approach to strengthening the body and treating disease. Herbs, however, can trigger side effects and can interact with other herbs, supplements, or medications. For these reasons, you should take herbs with care, under the supervision of a health care provider.
Do not take passionflower if you are pregnant or breastfeeding.
For others, passionflower is generally considered to be safe and nontoxic in recommended doses.
Possible Interactions
Passionflower may interact with the following medications:
Sedatives (drugs that cause sleepiness) -- Because of its calming effect, passionflower may make the effects of sedative medications stronger. These medications include:
Anticonvulsants such as phenytoin (Dilantin)
Barbiturates
Benzodiazepines such as alprazolam (Xanax) and diazepam (Valium)
Drugs for insomnia, such as zolpidem (Ambien), zaleplon (Sonata), eszopiclone (Lunesta), ramelteon (Rozerem)
Tricyclic antidepressants, such as amitriptyline (Elavil), amoxapine, doxepin (Sinequan), and nortriptyline (Pamelor)
Antiplatelets and anticoagulants (blood thinners) -- Passionflower may increase the amount of time blood needs to clot, so it could make the effects of blood thinning medications stronger and increase your risk of bleeding. Blood thinning drugs include:
Clopidogrel (Plavix)
Warfarin (Coumadin)
Aspirin
Monoamine oxidase inhibitors (MAO inhibitors or MAOIs) -- MAO inhibitors are an older class of antidepressants that are not often prescribed now. Theoretically, passionflower might increase the effects of MAO inhibitors, as well as their side effects, which can be dangerous. These drugs include:
Isocarboxazid (Marplan)
Phenelzine (Nardil)
Tranylcypromine (Parnate)
Supporting Research
Akhondzadeh S, Naghavi HR, Vazirian M, Shayeganpour A, Rashidi H, Khani M. Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam. J Clin Pharm Ther. 2001;26(5):369-373.
Akhondzadeh S. Passionflower in the treatment of opiates withdrawal: a double-blind randomized controlled trial. J Clin Pharm Ther. 2001;26(5):369-373.
Barbosa PR, Valvassori SS, Bordignon CL Jr, Kappel VD, Martins MR, Gavioli EC, et al. The aqueous extracts of Passiflora alata and Passiflora edulis reduce anxiety-related behaviors without affecting memory process in rats. J Med Food. 2008 Jun;11(2):282-8.
Blumenthal M, Goldberg A, Brinckmann J. Herbal Medicine: Expanded Commission E Monographs. Newton, MA: Integrative Medicine Communications; 2000:293-296.
Dhawan K, Kumar S, Sharma A. Anxiolytic activity of aerial and underground parts of Passifloraincarnata. Fitoterapia. 2001;72:922-6.
Dhawan K, Kumar S, Sharma A. Anti-anxiety studies on extracts of Passiflora incarnata Linneaus. J Ethnopharmacol. 2001;78:165-70.
Elsas SM, Rossi DJ, Raber J, White G, Seeley CA, Gregory WL, Mohr C, Pfankuch T, Soumyanath A. Passionflora incarnata L. (Passionflower) extracts elicit GABA currents in hippocampal neurons in vitro, and show anxiogenic and anticonvulsant effects in vivo, varying with extraction method. Phytomedicine. 2010;17(12):940-9.
Ernst E, ed. Passionflower. The Desktop Guide to Complementary and Alternative Medicine. Edinburgh: Mosby; 2001:140-141.
Grundmann O, Wang J, McGregor GP, Butterweck V. Anxiolytic Activity of a Phytochemically Characterized Passiflora incarnata Extract is Mediated via the GABAergic System. Planta Med. 2008 Dec;74(15):1769-73.
Lakhan SE, Vieira KF. Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review. Nutr J. 2010;9:42.
Larzelere MM, Wiseman P. Anxiety, depression, and insomnia. Prim Care. 2002 Jun;29(2):339-60, vii. Review.
Miyasaka L, Atallah A, Soares B. Passiflora for anxiety disorder. Cochrane Database Syst Rev. 2007 Jan 24;(1):CD004518.
Movafegh A, Alizadeh R, Hajimohamadi F, Esfehani F, Nejatfar M. Preoperative oral Passiflora incarnata reduces anxiety in ambulatory surgery patients: a double-blind, placebo-controlled study. Anesth Analg. 2008 Jun;106(6):1728-32.
Rotblatt M, Ziment I. Evidence-Based Herbal Medicine. Philadelphia, PA: Hanley & Belfus, Inc; 2002;294-297.
Sarris J. Herbal medicines in the treatment of psychiatric disorders: a systematic review. Phytother Res. 2007 Aug;21(8):703-16. Review.
Soulimani R, Younos C, Jarmouni S, Bousta D, Misslin R, Mortier F. Behavioural effects of
Watson RR, Zibadi S, Rafatpanah H, Jabbari F, Ghasemi R, Ghafari J, et al. Oral administration of the purple passion fruit peel extract reduces wheeze and cough and improves shortness of breath in adults with asthma. Nutr Res. 2008 Mar;28(3):166-71.
Alternative Names
Passiflora incarnata; Maypop
Version Info
Last Reviewed on 06/23/2011
Steven D. Ehrlich, NMD, Solutions Acupuncture, a private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
