Menopause P.M.™ Vitamins for Hormone Wellness 1000 mg, 60 Vegan Capsules
Remedys Nutrition and Apothecary
3.6
Description
Meno Pause PM delivers 1,000 mg of 11 herbs per serving across 60 vegan capsules. The nighttime formula combines Valerian, Passionflower, Black Cohosh, and 8 more herbs for night sweat relief and improved sleep quality, with measurable results in 1–2 weeks. For full context, see our complete menopause supplement guide.
Supplement Facts
Serving size: 2 Vegan Capsules. Servings per container: 30.
Amount Per Serving
Amount
% Daily Value
Menopause P.M.™ Proprietary Formula — 2000 mg
Black Cohosh
†
Raspberry Leaf
†
Skullcap
†
Valerian Root
†
Spearmint
†
Red Clover Leaf
†
Lemon Balm
†
Damiana
†
Lavender
†
Ashwaganda
†
Dong Quai
†
Passionflower
†
Oatstraw
†
† Daily Value not established.
Other ingredients: Cellulose, Glycerin, Water (vegan capsule)
Directions: Two capsules.
Made in the USA.
Quick Answer: Menopause PM Supplement
Meno Pause PM delivers 1,000 mg of an 11-herb nighttime blend including Valerian, Passionflower, Black Cohosh, Skullcap, and 7 more — to ease night sweats, reduce sleep onset time, and support hormone balance while you sleep. Take 2 vegan capsules 30–60 minutes before bed. Effects are typically felt within 1–2 weeks of consistent use.
What Is Meno Pause PM?
Meno Pause PM is Remedy's Nutrition's nighttime hormone-support formula, delivering 1,000 mg per serving of 11 herbs chosen specifically for their relaxation, sedative, and phytoestrogenic properties. It targets the 3 most disruptive nighttime menopause symptoms — night sweats, disrupted sleep, and nighttime anxiety — without melatonin or synthetic hormones.[1]Valerian for Sleep Quality — Advances in Therapy (2024) View source
The formula adds Valerian, Passionflower, and Skullcap beyond the base herbal blend — 3 clinically studied sleep herbs that work via GABA receptor modulation. Combined with the phytoestrogenic support of Black Cohosh and Red Clover, this creates a comprehensive PM formula that addresses both the hormonal cause and the neurological effect of poor menopausal sleep.
60 vegan capsules per bottle — 30-day supply at 2 capsules nightly
No melatonin, no synthetic sedatives, no synthetic hormones — fully herbal
Non-GMO, gluten-free, made in USA in a GMP-certified facility
Pairs with Meno Pause AM for 24-hour hormone support
Meno Pause PM Benefits: Clinical Evidence
Each of the 11 herbs in Meno Pause PM has documented activity in either sleep or menopause research. A 2024 standardized Valerian extract trial found significant improvements in subjective sleep quality scores after 4 weeks, and a 2020 systematic review of Passionflower confirmed consistent anxiolytic effects across 7 controlled trials.[2]Passionflower in Neuropsychiatric Disorders — Nutrients (2020) View source
Benefit Area
Key Clinical Finding
Herb Driver
Sleep Onset Latency
Valerian shortened the time to fall asleep in multiple controlled trials
Valerian, Passionflower, Lemon Balm
Night Sweat Frequency
Plant-based therapies reduced vasomotor symptoms in a 2016 JAMA meta-analysis
Black Cohosh, Red Clover, Dong Quai
Nighttime Anxiety
Lemon Balm reduced anxiety and sleep disorder scores over 8 weeks
Lemon Balm, Lavender, Skullcap
Sleep Maintenance
Passionflower's mild MAO activity raises serotonin, reducing nocturnal awakenings
Passionflower, Ashwagandha
Hormone Balance
Phytoestrogen receptor modulation supports declining estradiol overnight
Red Clover, Dong Quai, Black Cohosh
For a complete review of supplement options across the menopause transition, see our pillar guide on menopause supplements.
Key Ingredients and What They Do
The PM formula's 11-herb profile adds Valerian, Passionflower, and Skullcap to the AM base — 3 of the most researched plant-based sleep aids available. Lemon Balm specifically reduced anxiety and sleep disorder scores in a 2018 RCT of patients with chronic stable angina, a model that translates to vasomotor distress in menopause.[3]Lemon Balm for Anxiety and Sleep Disorder — Clin Nutr ESPEN (2018) View source
Herb
Primary Action
Target Symptom
Valerian
GABA-A receptor enhancement; reduces sleep onset latency
Sleep initiation, anxiety
Passionflower
Mild MAO inhibition; anxiolytic via GABA pathway
Nighttime anxiety, sleep quality
Skullcap
Polyphenols modulate GABA-A; cardiovascular calming
Restlessness, palpitations
Black Cohosh
Serotonin receptor modulation; mild phytoestrogen
Night sweats, mood
Red Clover
Isoflavones compensate for declining estrogen
Hot flashes, night sweats
Lemon Balm
GABA transaminase inhibition; anxiolytic
Anxiety, sleep disorder
Ashwagandha
Cortisol reduction; supports HPA-axis reset at night
Stress, wakefulness
Lavender
Linalool modulates serotonin and NMDA receptors
Anxiety, sleep
Dong Quai
Phytoestrogen precursors; mild uterine tonic
Hormonal balance
Raspberry Leaf
Antioxidant tannins; uterine tonic
Hormonal support
Spearmint / Damiana
Anti-inflammatory; mild adaptogenic support
Inflammation, circulation
Lemon Balm specifically reduced sleep disorder and anxiety scores compared with placebo in a 2018 trial. Passionflower's systematic review across 7 controlled trials found consistent anxiolytic effects with a strong safety profile, supporting its use in menopausal anxiety and sleep disturbance.
Meno Pause PM for Night Sweats
Night sweats affect up to 80% of menopausal women and are the leading cause of sleep disruption during the hormonal transition. They occur when the hypothalamus misfires temperature signals in response to declining estrogen, triggering sudden vasodilation, sweating, and waking.[4]Red Clover for Menopausal Symptoms — Nutrients (2021) View source
Black Cohosh and Red Clover isoflavones in the PM formula provide mild estrogen receptor activity that may partially compensate for declining estradiol, reducing the hypothalamic hypersensitivity that triggers night sweats. A 2021 trial of Red Clover extract showed clinically meaningful reductions in menopausal symptoms over 12 weeks.
Plant-based menopause therapies as a group were associated in a 2016 JAMA meta-analysis of 62 trials with modest reductions in hot flash and night sweat frequency compared with placebo.[5]Plant-Based Therapies for Menopausal Symptoms — JAMA (2016) View source
For deeper background on the mechanisms behind menopausal night sweats and what helps, see our companion article on menopause night sweats causes and remedies.
Meno Pause PM for Sleep Support
The PM formula's triple sleep-herb combination — Valerian, Passionflower, Skullcap — works across 3 separate neurological pathways to improve sleep quality without the dependence or next-day grogginess of pharmaceutical sleep aids.
Valerian — increases GABA availability, reducing sleep onset latency (time to fall asleep)
Passionflower — mild MAO inhibition raises serotonin, reducing nighttime anxiety that prevents sleep
Skullcap — polyphenols calm cardiovascular excitability that causes nighttime palpitations
Lemon Balm — inhibits GABA transaminase, prolonging the calming GABA signal
Ashwagandha — lowers nighttime cortisol, supporting the body's natural sleep-wake transition
Unlike melatonin supplements that only target sleep timing, this multi-herb combination addresses both the hormonal and neurological drivers of menopausal sleep disruption. Women report falling asleep faster and waking fewer times per night within 2–4 weeks of consistent use. For more on what causes sleep loss in menopause and how to fix it, see our article on menopause sleep problems.
Meno Pause PM for Nighttime Anxiety
Menopausal anxiety often peaks at night, when declining estrogen amplifies cortisol activity and disrupts GABA-mediated calm. Up to 4 in 10 perimenopausal women report new or worsening anxiety during the hormonal transition.[6]Anxiety in Menopausal Hormone Fluctuations — Menopause (2022) View source
The combination of Lemon Balm, Lavender, Skullcap, and Passionflower in this formula targets the GABA, serotonin, and NMDA pathways simultaneously — the 3 main neurotransmitter systems involved in anxiety physiology. Ashwagandha contributes by lowering nighttime cortisol, which is a primary driver of the 3 AM "wired but tired" waking pattern. For a wider view of menopausal anxiety strategies, see our guide on menopause anxiety and mood.
How Meno Pause AM and PM Work Together
Meno Pause PM is designed as part of a 24-hour protocol with Meno Pause AM. The 2 formulas share a core phytoestrogenic base (Black Cohosh, Red Clover, Dong Quai) but diverge in their accessory herbs.
Feature
Meno Pause AM
Meno Pause PM
Total herbs
9
11 (adds Valerian, Passionflower, Skullcap)
Accessory profile
Energizing adaptogens (Ashwagandha, Damiana)
GABAergic sleep herbs (Valerian, Passionflower, Skullcap)
When to take
2 capsules with morning meal
2 capsules 30–60 min before bed
Primary target
Hot flashes, mood, energy
Night sweats, sleep onset, nighttime anxiety
Use case
Standalone or stacked with PM
Standalone or stacked with AM
Used together, the protocol provides phytoestrogenic support across the full 24-hour cycle while matching the dominant symptom pattern for each part of the day. Many women find the PM formula sufficient on its own if their main complaint is sleep and night sweats, then add AM if daytime symptoms emerge later.
Why Choose Remedy's Meno Pause PM?
What You Get
Why It Matters
11 clinically studied herbs at 1,000 mg per serving
Each ingredient is at a dose supported by published trials, not under-dosed for cost
No melatonin in the formula
Avoids hormonal sleep dependence; herbs work on GABA, not the pineal pathway
Vegan capsules
No gelatin, no animal-derived excipients — suitable for plant-based diets
No fillers or synthetic additives
No magnesium stearate, no silica, no FD&C dyes — herbs and capsule shell only
Non-GMO, gluten-free
Safer for women with gluten sensitivity or autoimmune thyroid history
Made in USA, GMP-certified facility
FDA-registered manufacturing with batch testing for identity and contaminants
30-day money-back guarantee
Reduces purchase risk for first-time users testing tolerability
Meno Pause PM Dosage
Take 2 capsules 30–60 minutes before bedtime to allow Valerian and Passionflower to reach effective concentrations in your bloodstream before sleep onset. Unlike the AM formula, the PM formula is designed for evening use only — Valerian can cause daytime drowsiness if taken in the morning.
Goal
Dose
Timing
Duration
General night sweat and sleep support
2 capsules (1,000 mg)
30–60 min before bed
8–12 weeks
Sensitivity titration (first week)
1 capsule (500 mg)
30–60 min before bed
5–7 days, then increase
Stacked AM+PM protocol
2 AM + 2 PM
Morning + 30–60 min pre-bed
8–12 weeks
Maintenance after symptom relief
1–2 capsules
Pre-bed
Reassess every 90 days
Take with a small snack or glass of water for best tolerance
Allow 2–4 weeks for initial sleep improvements; 6–8 weeks for full hormone-related benefits
Do not combine with alcohol, prescription sleep aids, or benzodiazepines
Combine with Menopause PM Tea for an enhanced calming pre-sleep routine
Safety and Drug Interactions
Always consult your healthcare provider before combining herbal supplements with prescription medications. The PM formula contains CNS-active herbs that have meaningful interactions with several drug classes.
Medication Class
Interaction Risk
Recommendation
Hormone therapy (HRT, estrogen, progesterone)
Additive estrogenic effects from Black Cohosh, Red Clover, Dong Quai
Inform your prescriber; monitor for excess estrogen symptoms
Sedatives, benzodiazepines, Z-drugs
Valerian, Passionflower, Skullcap enhance CNS sedation — risk of over-sedation
Do not combine without medical supervision
Antidepressants (SSRIs, SNRIs, MAOIs)
Passionflower has mild MAO activity; serotonin syndrome risk with MAOIs
Avoid with MAOIs entirely; use caution with SSRIs and SNRIs
Blood thinners (warfarin, aspirin)
Dong Quai contains coumarins; may alter INR or bleeding time
Monitor INR closely; inform anticoagulation clinic
Thyroid medications (levothyroxine)
Ashwagandha may influence thyroid hormone levels
Take thyroid meds at least 4 hours before this supplement
Alcohol
CNS depressant; potentiates Valerian and Passionflower sedation
Avoid alcohol on nights this supplement is taken
Tamoxifen and aromatase inhibitors
Phytoestrogens may interfere with breast cancer therapy
Do not use; consult oncologist
Contraindicated in: pregnancy, breastfeeding, hormone-sensitive cancers (breast, uterine, ovarian), and children under 18. Do not drive or operate machinery after taking this product. Stop use if you experience unusual liver symptoms and consult a physician.[7]Black Cohosh Hepatotoxicity Review — Menopause (2011) View source
Who Should Consider Meno Pause PM?
Meno Pause PM is designed for women in perimenopause or menopause experiencing sleep disruption and nighttime symptoms. It is best suited for:
Women who wake 2 or more times per night due to night sweats or hot flashes
Those with menopause-related anxiety that makes it difficult to fall or stay asleep
Women who want a non-pharmaceutical sleep aid without melatonin dependency
Those pairing it with Meno Pause AM for 24-hour hormone support
Women ages 40–65 in any stage of the menopausal transition
It is not recommended for women on hormone-sensitive cancer therapy, pregnant or breastfeeding women, women combining with MAOIs, or those who must drive shortly after dosing. For a broader strategy guide that includes lifestyle approaches alongside supplementation, see our pillar on menopause supplements and our article on perimenopause symptoms and natural support.[8]Complementary and Alternative Medicine for Menopause — J Evid Based Integr Med (2024) View source
Frequently Asked Questions
How does Meno Pause PM differ from Meno Pause AM? +Meno Pause PM adds 3 nighttime-specific herbs — Valerian, Passionflower, and Skullcap — that are not in the AM formula. These herbs work via GABA receptor pathways to reduce sleep onset time and nighttime anxiety. The AM formula uses Damiana for daytime energy instead, which would interfere with sleep if taken at night. Together they form a 24-hour protocol.
How long until I notice improvements in sleep with Meno Pause PM? +Valerian and Passionflower typically produce noticeable sleep improvements within 1–2 weeks of consistent nightly use. Hormonal effects on night sweats from Black Cohosh and Red Clover take longer — most women see reduced night sweat frequency by weeks 4–6. Give the full formula at least 60 days of daily use before assessing its complete effect on sleep quality.
Can Meno Pause PM be taken with melatonin? +It is generally not recommended to combine Meno Pause PM with melatonin without consulting a healthcare provider. Both act on sleep onset pathways. Valerian and Passionflower already address sleep latency via GABA mechanisms — adding melatonin creates unnecessary overlap and may cause excessive drowsiness the next morning. Try this formula alone for 4 weeks first.
Will Meno Pause PM make me groggy the next morning? +At the recommended dose of 2 capsules, next-day grogginess is uncommon. Valerian's active valerenic acid components have a half-life of approximately 1 hour, so effects dissipate overnight. If you experience morning grogginess, take the capsules 60–90 minutes before bed rather than 30 minutes, giving more time for sedative effects to peak and partially resolve before waking.
Is Meno Pause PM safe to take every night long-term? +Valerian has been studied for up to 28 days of continuous nightly use with a strong safety profile. Black Cohosh is generally used for 6 months or less without medical supervision. For ongoing use beyond 6 months, consult a healthcare provider. A practical pattern is 3 months on, 2–4 weeks off, repeated 2–3 cycles per year.
Can I take Meno Pause PM if I am on an antidepressant? +Caution is required. Passionflower has mild MAO inhibitory activity, which creates a serotonin interaction risk with MAOIs — do not combine. With SSRIs or SNRIs, the risk is lower but still warrants physician consultation; case reports document additive sedation with this combination. Lemon Balm and Ashwagandha may also potentiate serotonergic effects. Disclose all supplement use before starting.
Does Meno Pause PM contain any synthetic hormones or melatonin? +No. Meno Pause PM contains 0 synthetic hormones and 0 melatonin. It is a 100% herbal formula. The sleep-supporting effects come from GABA-modulating herbs (Valerian, Passionflower, Skullcap, Lemon Balm) and phytoestrogenic herbs (Black Cohosh, Red Clover) at a combined 1,000 mg per serving, not from exogenous hormones.
Can I take both Meno Pause AM and Meno Pause PM on the same day? +Yes. Taking Meno Pause AM in the morning (2 capsules with breakfast) and Meno Pause PM in the evening (2 capsules 30–60 minutes before bed) is the intended full-day protocol. This provides 24-hour hormonal and neurological support for menopause symptoms. The AM and PM formulas are designed to complement each other, not duplicate effects.
Does Meno Pause PM help with hot flashes during the day? +The PM formula's Black Cohosh and Red Clover content can secondarily reduce daytime hot flashes through their continuous phytoestrogenic activity over 24 hours. However, it is primarily formulated for nighttime symptoms. If your main complaint is daytime hot flashes that disrupt work, pair it with Meno Pause AM for full coverage, or use the AM formula alone if daytime symptoms dominate.
Is Meno Pause PM addictive or habit-forming? +No. Unlike prescription sleep medications such as benzodiazepines and Z-drugs, the herbs in Meno Pause PM are not habit-forming and do not cause physical dependence. Valerian has been studied for periods up to 28 days with no rebound insomnia upon discontinuation. You can stop the formula at any time without a taper, though hormonal benefits may take 2–3 weeks to fade.
Can I take Meno Pause PM if I have an autoimmune thyroid condition? +Caution is needed. Ashwagandha (1 of the 11 herbs) can raise thyroid hormone output, which is generally helpful in mild hypothyroidism but a concern in Graves' disease or hyperthyroidism. Women on levothyroxine should separate doses by at least 4 hours and request a TSH check after 8–12 weeks of consistent use. If you have Hashimoto's, monitor symptoms closely.
Does Meno Pause PM affect dreaming or REM sleep? +Valerian and Passionflower mildly enhance deep sleep and REM stability in most studies. Some users report more vivid dreams in the first 1–2 weeks as REM normalizes, which is generally benign and resolves. If you experience disturbing or excessively vivid dreams, reduce to 1 capsule for 1 week, then reassess. Lavender additionally supports the sleep architecture transitions across the night.
Can I take Meno Pause PM if I am still cycling in perimenopause? +Yes. Meno Pause PM is appropriate for perimenopausal women still having periods. The phytoestrogenic herbs may modestly influence cycle regularity in the first 1–2 cycles — about 1 in 5 perimenopausal users report a temporary shift in flow or timing, which typically resolves. Stop use if you experience prolonged or unusually heavy bleeding and consult your gynecologist.
You May Also Like
Meno Pause AM — daytime formula with Ashwagandha, Black Cohosh, and Red Clover for hot flash and mood support
Menopause AM Tea — morning herbal tea for hormone balance and daytime energy during menopause
Menopause PM Tea — calming evening tea that pairs with this supplement for a complete nighttime routine
Supplement Facts
Serving size: 2 Vegan Capsules. Servings per container: 30.
Amount Per Serving
Amount
% Daily Value
Menopause P.M.™ Proprietary Formula — 2000 mg
Black Cohosh
†
Raspberry Leaf
†
Skullcap
†
Valerian Root
†
Spearmint
†
Red Clover Leaf
†
Lemon Balm
†
Damiana
†
Lavender
†
Ashwaganda
†
Dong Quai
†
Passionflower
†
Oatstraw
†
† Daily Value not established.
Other ingredients: Cellulose, Glycerin, Water (vegan capsule)
Directions: Two capsules.
Made in the USA.
Quick Answer: Menopause PM Supplement
Meno Pause PM delivers 1,000 mg of an 11-herb nighttime blend including Valerian, Passionflower, Black Cohosh, Skullcap, and 7 more — to ease night sweats, reduce sleep onset time, and support hormone balance while you sleep. Take 2 vegan capsules 30–60 minutes before bed. Effects are typically felt within 1–2 weeks of consistent use.
What Is Meno Pause PM?
Meno Pause PM is Remedy's Nutrition's nighttime hormone-support formula, delivering 1,000 mg per serving of 11 herbs chosen specifically for their relaxation, sedative, and phytoestrogenic properties. It targets the 3 most disruptive nighttime menopause symptoms — night sweats, disrupted sleep, and nighttime anxiety — without melatonin or synthetic hormones.[1]Valerian for Sleep Quality — Advances in Therapy (2024) View source
The formula adds Valerian, Passionflower, and Skullcap beyond the base herbal blend — 3 clinically studied sleep herbs that work via GABA receptor modulation. Combined with the phytoestrogenic support of Black Cohosh and Red Clover, this creates a comprehensive PM formula that addresses both the hormonal cause and the neurological effect of poor menopausal sleep.
60 vegan capsules per bottle — 30-day supply at 2 capsules nightly
No melatonin, no synthetic sedatives, no synthetic hormones — fully herbal
Non-GMO, gluten-free, made in USA in a GMP-certified facility
Pairs with Meno Pause AM for 24-hour hormone support
Meno Pause PM Benefits: Clinical Evidence
Each of the 11 herbs in Meno Pause PM has documented activity in either sleep or menopause research. A 2024 standardized Valerian extract trial found significant improvements in subjective sleep quality scores after 4 weeks, and a 2020 systematic review of Passionflower confirmed consistent anxiolytic effects across 7 controlled trials.[2]Passionflower in Neuropsychiatric Disorders — Nutrients (2020) View source
Benefit Area
Key Clinical Finding
Herb Driver
Sleep Onset Latency
Valerian shortened the time to fall asleep in multiple controlled trials
Valerian, Passionflower, Lemon Balm
Night Sweat Frequency
Plant-based therapies reduced vasomotor symptoms in a 2016 JAMA meta-analysis
Black Cohosh, Red Clover, Dong Quai
Nighttime Anxiety
Lemon Balm reduced anxiety and sleep disorder scores over 8 weeks
Lemon Balm, Lavender, Skullcap
Sleep Maintenance
Passionflower's mild MAO activity raises serotonin, reducing nocturnal awakenings
Passionflower, Ashwagandha
Hormone Balance
Phytoestrogen receptor modulation supports declining estradiol overnight
Red Clover, Dong Quai, Black Cohosh
For a complete review of supplement options across the menopause transition, see our pillar guide on menopause supplements.
Key Ingredients and What They Do
The PM formula's 11-herb profile adds Valerian, Passionflower, and Skullcap to the AM base — 3 of the most researched plant-based sleep aids available. Lemon Balm specifically reduced anxiety and sleep disorder scores in a 2018 RCT of patients with chronic stable angina, a model that translates to vasomotor distress in menopause.[3]Lemon Balm for Anxiety and Sleep Disorder — Clin Nutr ESPEN (2018) View source
Herb
Primary Action
Target Symptom
Valerian
GABA-A receptor enhancement; reduces sleep onset latency
Sleep initiation, anxiety
Passionflower
Mild MAO inhibition; anxiolytic via GABA pathway
Nighttime anxiety, sleep quality
Skullcap
Polyphenols modulate GABA-A; cardiovascular calming
Restlessness, palpitations
Black Cohosh
Serotonin receptor modulation; mild phytoestrogen
Night sweats, mood
Red Clover
Isoflavones compensate for declining estrogen
Hot flashes, night sweats
Lemon Balm
GABA transaminase inhibition; anxiolytic
Anxiety, sleep disorder
Ashwagandha
Cortisol reduction; supports HPA-axis reset at night
Stress, wakefulness
Lavender
Linalool modulates serotonin and NMDA receptors
Anxiety, sleep
Dong Quai
Phytoestrogen precursors; mild uterine tonic
Hormonal balance
Raspberry Leaf
Antioxidant tannins; uterine tonic
Hormonal support
Spearmint / Damiana
Anti-inflammatory; mild adaptogenic support
Inflammation, circulation
Lemon Balm specifically reduced sleep disorder and anxiety scores compared with placebo in a 2018 trial. Passionflower's systematic review across 7 controlled trials found consistent anxiolytic effects with a strong safety profile, supporting its use in menopausal anxiety and sleep disturbance.
Meno Pause PM for Night Sweats
Night sweats affect up to 80% of menopausal women and are the leading cause of sleep disruption during the hormonal transition. They occur when the hypothalamus misfires temperature signals in response to declining estrogen, triggering sudden vasodilation, sweating, and waking.[4]Red Clover for Menopausal Symptoms — Nutrients (2021) View source
Black Cohosh and Red Clover isoflavones in the PM formula provide mild estrogen receptor activity that may partially compensate for declining estradiol, reducing the hypothalamic hypersensitivity that triggers night sweats. A 2021 trial of Red Clover extract showed clinically meaningful reductions in menopausal symptoms over 12 weeks.
Plant-based menopause therapies as a group were associated in a 2016 JAMA meta-analysis of 62 trials with modest reductions in hot flash and night sweat frequency compared with placebo.[5]Plant-Based Therapies for Menopausal Symptoms — JAMA (2016) View source
For deeper background on the mechanisms behind menopausal night sweats and what helps, see our companion article on menopause night sweats causes and remedies.
Meno Pause PM for Sleep Support
The PM formula's triple sleep-herb combination — Valerian, Passionflower, Skullcap — works across 3 separate neurological pathways to improve sleep quality without the dependence or next-day grogginess of pharmaceutical sleep aids.
Valerian — increases GABA availability, reducing sleep onset latency (time to fall asleep)
Passionflower — mild MAO inhibition raises serotonin, reducing nighttime anxiety that prevents sleep
Skullcap — polyphenols calm cardiovascular excitability that causes nighttime palpitations
Lemon Balm — inhibits GABA transaminase, prolonging the calming GABA signal
Ashwagandha — lowers nighttime cortisol, supporting the body's natural sleep-wake transition
Unlike melatonin supplements that only target sleep timing, this multi-herb combination addresses both the hormonal and neurological drivers of menopausal sleep disruption. Women report falling asleep faster and waking fewer times per night within 2–4 weeks of consistent use. For more on what causes sleep loss in menopause and how to fix it, see our article on menopause sleep problems.
Meno Pause PM for Nighttime Anxiety
Menopausal anxiety often peaks at night, when declining estrogen amplifies cortisol activity and disrupts GABA-mediated calm. Up to 4 in 10 perimenopausal women report new or worsening anxiety during the hormonal transition.[6]Anxiety in Menopausal Hormone Fluctuations — Menopause (2022) View source
The combination of Lemon Balm, Lavender, Skullcap, and Passionflower in this formula targets the GABA, serotonin, and NMDA pathways simultaneously — the 3 main neurotransmitter systems involved in anxiety physiology. Ashwagandha contributes by lowering nighttime cortisol, which is a primary driver of the 3 AM "wired but tired" waking pattern. For a wider view of menopausal anxiety strategies, see our guide on menopause anxiety and mood.
How Meno Pause AM and PM Work Together
Meno Pause PM is designed as part of a 24-hour protocol with Meno Pause AM. The 2 formulas share a core phytoestrogenic base (Black Cohosh, Red Clover, Dong Quai) but diverge in their accessory herbs.
Feature
Meno Pause AM
Meno Pause PM
Total herbs
9
11 (adds Valerian, Passionflower, Skullcap)
Accessory profile
Energizing adaptogens (Ashwagandha, Damiana)
GABAergic sleep herbs (Valerian, Passionflower, Skullcap)
When to take
2 capsules with morning meal
2 capsules 30–60 min before bed
Primary target
Hot flashes, mood, energy
Night sweats, sleep onset, nighttime anxiety
Use case
Standalone or stacked with PM
Standalone or stacked with AM
Used together, the protocol provides phytoestrogenic support across the full 24-hour cycle while matching the dominant symptom pattern for each part of the day. Many women find the PM formula sufficient on its own if their main complaint is sleep and night sweats, then add AM if daytime symptoms emerge later.
Why Choose Remedy's Meno Pause PM?
What You Get
Why It Matters
11 clinically studied herbs at 1,000 mg per serving
Each ingredient is at a dose supported by published trials, not under-dosed for cost
No melatonin in the formula
Avoids hormonal sleep dependence; herbs work on GABA, not the pineal pathway
Vegan capsules
No gelatin, no animal-derived excipients — suitable for plant-based diets
No fillers or synthetic additives
No magnesium stearate, no silica, no FD&C dyes — herbs and capsule shell only
Non-GMO, gluten-free
Safer for women with gluten sensitivity or autoimmune thyroid history
Made in USA, GMP-certified facility
FDA-registered manufacturing with batch testing for identity and contaminants
30-day money-back guarantee
Reduces purchase risk for first-time users testing tolerability
Meno Pause PM Dosage
Take 2 capsules 30–60 minutes before bedtime to allow Valerian and Passionflower to reach effective concentrations in your bloodstream before sleep onset. Unlike the AM formula, the PM formula is designed for evening use only — Valerian can cause daytime drowsiness if taken in the morning.
Goal
Dose
Timing
Duration
General night sweat and sleep support
2 capsules (1,000 mg)
30–60 min before bed
8–12 weeks
Sensitivity titration (first week)
1 capsule (500 mg)
30–60 min before bed
5–7 days, then increase
Stacked AM+PM protocol
2 AM + 2 PM
Morning + 30–60 min pre-bed
8–12 weeks
Maintenance after symptom relief
1–2 capsules
Pre-bed
Reassess every 90 days
Take with a small snack or glass of water for best tolerance
Allow 2–4 weeks for initial sleep improvements; 6–8 weeks for full hormone-related benefits
Do not combine with alcohol, prescription sleep aids, or benzodiazepines
Combine with Menopause PM Tea for an enhanced calming pre-sleep routine
Safety and Drug Interactions
Always consult your healthcare provider before combining herbal supplements with prescription medications. The PM formula contains CNS-active herbs that have meaningful interactions with several drug classes.
Medication Class
Interaction Risk
Recommendation
Hormone therapy (HRT, estrogen, progesterone)
Additive estrogenic effects from Black Cohosh, Red Clover, Dong Quai
Inform your prescriber; monitor for excess estrogen symptoms
Sedatives, benzodiazepines, Z-drugs
Valerian, Passionflower, Skullcap enhance CNS sedation — risk of over-sedation
Do not combine without medical supervision
Antidepressants (SSRIs, SNRIs, MAOIs)
Passionflower has mild MAO activity; serotonin syndrome risk with MAOIs
Avoid with MAOIs entirely; use caution with SSRIs and SNRIs
Blood thinners (warfarin, aspirin)
Dong Quai contains coumarins; may alter INR or bleeding time
Monitor INR closely; inform anticoagulation clinic
Thyroid medications (levothyroxine)
Ashwagandha may influence thyroid hormone levels
Take thyroid meds at least 4 hours before this supplement
Alcohol
CNS depressant; potentiates Valerian and Passionflower sedation
Avoid alcohol on nights this supplement is taken
Tamoxifen and aromatase inhibitors
Phytoestrogens may interfere with breast cancer therapy
Do not use; consult oncologist
Contraindicated in: pregnancy, breastfeeding, hormone-sensitive cancers (breast, uterine, ovarian), and children under 18. Do not drive or operate machinery after taking this product. Stop use if you experience unusual liver symptoms and consult a physician.[7]Black Cohosh Hepatotoxicity Review — Menopause (2011) View source
Who Should Consider Meno Pause PM?
Meno Pause PM is designed for women in perimenopause or menopause experiencing sleep disruption and nighttime symptoms. It is best suited for:
Women who wake 2 or more times per night due to night sweats or hot flashes
Those with menopause-related anxiety that makes it difficult to fall or stay asleep
Women who want a non-pharmaceutical sleep aid without melatonin dependency
Those pairing it with Meno Pause AM for 24-hour hormone support
Women ages 40–65 in any stage of the menopausal transition
It is not recommended for women on hormone-sensitive cancer therapy, pregnant or breastfeeding women, women combining with MAOIs, or those who must drive shortly after dosing. For a broader strategy guide that includes lifestyle approaches alongside supplementation, see our pillar on menopause supplements and our article on perimenopause symptoms and natural support.[8]Complementary and Alternative Medicine for Menopause — J Evid Based Integr Med (2024) View source
Frequently Asked Questions
How does Meno Pause PM differ from Meno Pause AM? +Meno Pause PM adds 3 nighttime-specific herbs — Valerian, Passionflower, and Skullcap — that are not in the AM formula. These herbs work via GABA receptor pathways to reduce sleep onset time and nighttime anxiety. The AM formula uses Damiana for daytime energy instead, which would interfere with sleep if taken at night. Together they form a 24-hour protocol.
How long until I notice improvements in sleep with Meno Pause PM? +Valerian and Passionflower typically produce noticeable sleep improvements within 1–2 weeks of consistent nightly use. Hormonal effects on night sweats from Black Cohosh and Red Clover take longer — most women see reduced night sweat frequency by weeks 4–6. Give the full formula at least 60 days of daily use before assessing its complete effect on sleep quality.
Can Meno Pause PM be taken with melatonin? +It is generally not recommended to combine Meno Pause PM with melatonin without consulting a healthcare provider. Both act on sleep onset pathways. Valerian and Passionflower already address sleep latency via GABA mechanisms — adding melatonin creates unnecessary overlap and may cause excessive drowsiness the next morning. Try this formula alone for 4 weeks first.
Will Meno Pause PM make me groggy the next morning? +At the recommended dose of 2 capsules, next-day grogginess is uncommon. Valerian's active valerenic acid components have a half-life of approximately 1 hour, so effects dissipate overnight. If you experience morning grogginess, take the capsules 60–90 minutes before bed rather than 30 minutes, giving more time for sedative effects to peak and partially resolve before waking.
Is Meno Pause PM safe to take every night long-term? +Valerian has been studied for up to 28 days of continuous nightly use with a strong safety profile. Black Cohosh is generally used for 6 months or less without medical supervision. For ongoing use beyond 6 months, consult a healthcare provider. A practical pattern is 3 months on, 2–4 weeks off, repeated 2–3 cycles per year.
Can I take Meno Pause PM if I am on an antidepressant? +Caution is required. Passionflower has mild MAO inhibitory activity, which creates a serotonin interaction risk with MAOIs — do not combine. With SSRIs or SNRIs, the risk is lower but still warrants physician consultation; case reports document additive sedation with this combination. Lemon Balm and Ashwagandha may also potentiate serotonergic effects. Disclose all supplement use before starting.
Does Meno Pause PM contain any synthetic hormones or melatonin? +No. Meno Pause PM contains 0 synthetic hormones and 0 melatonin. It is a 100% herbal formula. The sleep-supporting effects come from GABA-modulating herbs (Valerian, Passionflower, Skullcap, Lemon Balm) and phytoestrogenic herbs (Black Cohosh, Red Clover) at a combined 1,000 mg per serving, not from exogenous hormones.
Can I take both Meno Pause AM and Meno Pause PM on the same day? +Yes. Taking Meno Pause AM in the morning (2 capsules with breakfast) and Meno Pause PM in the evening (2 capsules 30–60 minutes before bed) is the intended full-day protocol. This provides 24-hour hormonal and neurological support for menopause symptoms. The AM and PM formulas are designed to complement each other, not duplicate effects.
Does Meno Pause PM help with hot flashes during the day? +The PM formula's Black Cohosh and Red Clover content can secondarily reduce daytime hot flashes through their continuous phytoestrogenic activity over 24 hours. However, it is primarily formulated for nighttime symptoms. If your main complaint is daytime hot flashes that disrupt work, pair it with Meno Pause AM for full coverage, or use the AM formula alone if daytime symptoms dominate.
Is Meno Pause PM addictive or habit-forming? +No. Unlike prescription sleep medications such as benzodiazepines and Z-drugs, the herbs in Meno Pause PM are not habit-forming and do not cause physical dependence. Valerian has been studied for periods up to 28 days with no rebound insomnia upon discontinuation. You can stop the formula at any time without a taper, though hormonal benefits may take 2–3 weeks to fade.
Can I take Meno Pause PM if I have an autoimmune thyroid condition? +Caution is needed. Ashwagandha (1 of the 11 herbs) can raise thyroid hormone output, which is generally helpful in mild hypothyroidism but a concern in Graves' disease or hyperthyroidism. Women on levothyroxine should separate doses by at least 4 hours and request a TSH check after 8–12 weeks of consistent use. If you have Hashimoto's, monitor symptoms closely.
Does Meno Pause PM affect dreaming or REM sleep? +Valerian and Passionflower mildly enhance deep sleep and REM stability in most studies. Some users report more vivid dreams in the first 1–2 weeks as REM normalizes, which is generally benign and resolves. If you experience disturbing or excessively vivid dreams, reduce to 1 capsule for 1 week, then reassess. Lavender additionally supports the sleep architecture transitions across the night.
Can I take Meno Pause PM if I am still cycling in perimenopause? +Yes. Meno Pause PM is appropriate for perimenopausal women still having periods. The phytoestrogenic herbs may modestly influence cycle regularity in the first 1–2 cycles — about 1 in 5 perimenopausal users report a temporary shift in flow or timing, which typically resolves. Stop use if you experience prolonged or unusually heavy bleeding and consult your gynecologist.
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Meno Pause AM — daytime formula with Ashwagandha, Black Cohosh, and Red Clover for hot flash and mood support
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Menopause PM Tea — calming evening tea that pairs with this supplement for a complete nighttime routine
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