L-Lysine & HCL 1000 mg, 60 Vegan Capsules

What L-Lysine Is
L-lysine is 1 of the 9 essential amino acids: your body cannot make it, so it has to come from food or a supplement. Remedy's L-Lysine supplies 1000 mg per vegan capsule, with 60 capsules per bottle, as L-lysine hydrochloride, the stable salt form used in supplements.
Most people buy lysine for cold sores. The evidence for that is real, small and split by dose, and this page shows it rather than summarising it away.

1000 mg per capsule: As stated on the label.

60 capsules: 2 months at the label's 1 capsule a day.

The full evidence map is in what L-lysine is good for.

Supplement Facts

Amount Per Serving
Amount
% Daily Value

L-Lysine
1000 mg
*

HCL
25 mcg
*

* Daily Value not established. Both lines are reproduced exactly as printed on the label.
Non-GMO, vegan, gluten free, no additives, no preservatives. Made in the USA.

What “& HCL” Means
The & HCL in the name is the hydrochloride salt, written the way the label writes it. L-lysine hydrochloride is 1 ingredient, not lysine plus a second substance, and it is not betaine HCl or added stomach acid.
The salt is about 80% lysine by weight: 146.19 for lysine against 182.65 for the hydrochloride.[1]L-Lysine, CID 5962, molecular weight 146.19 — PubChem, National Library of Medicine View source[2]L-Lysine monohydrochloride, CID 69568, molecular weight 182.65 — PubChem, National Library of Medicine View source That makes the label's wording matter.

If the label counts
Lysine per capsule
Lysine in 3 capsules

L-lysine hydrochloride, 1000 mg
About 800 mg
About 2,400 mg

L-lysine itself, 1000 mg
1,000 mg
3,000 mg

The HCL 25 mcg line: In 1000 mg of the salt, the hydrochloride part weighs about 200 mg, so this line does not describe a separate dose.

What we say until it is confirmed: Each capsule holds 800 to 1,000 mg of lysine.

How that maps onto trial doses is worked through in how much lysine to take per day.
What the Evidence Actually Shows
Rather than print a benefits list, we would rather print the shape of the literature. These counts came off PubMed on 2026-10-08 and anyone can rerun them.

What PubMed holds on lysine
Count

Records with lysine in the title or abstract
92,630

Records on lysine as a supplement or nutrient
3,806

Of those, tagged as human
732

Of those, tagged as clinical trials
86

Records pairing lysine with herpes
212

Herpes records tagged as trials (newest 1987)
9

Lysine is heavily studied as a molecule and lightly trialled as a supplement. For cold sores, the newest placebo-controlled trial is from 1987.
This is the use most people buy lysine for, and the results depend on the dose.

Daily amount
Result

624 mg of the salt
Not effective

About 1,000 mg, 3 trials
No effect on overall recurrence rate

1,248 mg of the salt, plus a low-arginine diet
Fewer recurrences

3,000 mg, 6 months
2.4 fewer outbreaks, milder, faster healing

The 1987 trial gave 1,000 mg of lysine 3 times a day for 6 months and averaged 2.4 fewer outbreaks.[3]Success of L-lysine therapy in frequently recurrent herpes simplex infection — Dermatologica (1987) View source The 2015 Cochrane review of prevention treatments found no evidence of efficacy for lysine.[4]Interventions for prevention of herpes simplex labialis (cold sores on the lips) — Cochrane Database of Systematic Reviews (2015) View source We make no cold sore claim for this product. Every trial is in lysine for cold sores and herpes.
The Arginine Question
The lysine idea began in cell cultures, where herpes failed to replicate without arginine and lysine partly inhibited it.[5]Amino acid requirements of herpes simplex virus in human cells — Journal of Bacteriology (1964) View source

Whether food ratios matter is covered in lysine vs arginine.
Lysine From Food
Adults need about 30 mg of lysine per kg a day, roughly 2,100 mg at 70 kg, and most mixed diets supply several times that. Dairy, fish, meat, eggs and legumes are the main sources; cereals are low.

1 capsule: 800 to 1,000 mg on top of food.

Vegan sources and the full list are in foods high in lysine.
Stress and Anxiety
Three human trials reported calmer stress responses, and 2 of them gave lysine with an equal dose of arginine, 2.64 to 3 g of each.[6]Oral treatment with L-lysine and L-arginine reduces anxiety and basal cortisol levels in healthy humans — Biomedical Research (2007) View source They do not test a lysine-only capsule, so we make no anxiety claim.

The trial details are in lysine for anxiety and stress.
Safety and Who Should Be Careful
A 2019 review of 71 studies found mainly mild stomach symptoms, no more often than on control, and proposed 6,000 mg a day as a provisional no-adverse-effect level.[7]Safety assessment of L-lysine oral intake: a systematic review — Amino Acids (2019) View source The cautions are about what was never tested.

Situation
Position

Kidney disease or reduced kidney function
Ask your doctor first; never studied

Pregnant or breastfeeding
Ask first; 0 randomized trials found

Taking high-dose calcium
Ask first; lysine raised calcium absorption

Taking gentamicin or another aminoglycoside
Ask first; worse kidney injury in rats

Frequent, severe or eye-area cold sores
See a doctor; antivirals have better evidence

One 1996 case linked lysine to kidney damage that progressed to chronic kidney failure.[8]Fanconi's syndrome and tubulointerstitial nephritis in association with L-lysine ingestion — American Journal of Kidney Diseases (1996) View source The full list is in lysine side effects.
How to Take It
There is no official dose for lysine. The label directions are 1 capsule daily.

Trial doses for cold sores: About 1,000 to 3,000 mg a day, split through the day.

Timing: 0 trials compared morning with evening; with food suits a sensitive stomach.

Why Choose Remedy's L-Lysine
No trial makes one lysine capsule better than another, so the honest differentiators are what is in the bottle and what the page is willing to say.

1000 mg per capsule: A fixed, countable amount.

What we will not say matters as much as what we will, and on this page that means no disease claim of any kind.
Frequently Asked Questions

What does & HCL mean in the product name? +
It means the lysine is in its hydrochloride salt form, L-lysine HCl, the stable form used in supplements. It is 1 ingredient, about 80% lysine by weight.

How much lysine is in 1 capsule? +
The label states 1000 mg. If that counts the hydrochloride salt, the lysine content is about 800 mg, so we state 800 to 1,000 mg until the wording is confirmed.

How many capsules match the cold sore trials? +
The most positive trial used 3,000 mg of lysine a day: 3 capsules if 1000 mg counts lysine, or nearly 4 if it counts the salt. Ask your doctor first.

Is this product vegan? +
The label states vegan and lists 3 capsule ingredients: cellulose, glycerin and water. The lysine itself is not from an animal source.

How long does 1 bottle last? +
Sixty capsules last 60 days at the label's 1 capsule a day, or 20 days at 3 a day.

Will it stop my cold sores? +
We cannot promise that. Trials at about 1,000 mg a day mostly failed, 3,000 mg helped in 1 trial of 52 people, and a 2015 Cochrane review found no evidence of efficacy for prevention.

Can I take it with a calcium supplement? +
Ask first if you take high-dose calcium. In 1 study, 800 mg of lysine a day raised calcium absorption in 45 people.

Is it safe for the kidneys? +
Trials in healthy adults have not shown a kidney problem, but 1 case of kidney damage was published in 1996 and kidney disease was never studied. Ask your doctor first if you have it.

Does it contain arginine? +
No. The label lists 1 active ingredient, L-lysine, and no arginine.

Is it suitable during pregnancy? +
We found 0 randomized trials of lysine supplements in pregnancy, so ask your obstetrician before taking it.

What time of day should I take it? +
0 trials compared timing. The label says 1 capsule daily; taking it with food is a reasonable default if your stomach is sensitive.

Does it help with anxiety? +
The anxiety trials gave 2.64 to 3 g of lysine with an equal dose of arginine, so they do not test this product. We make no anxiety claim.

You May Also Like

Zinc Lozenges 15 mg — a separate lozenge kept for the cold season

L-Theanine 1000 mg — a different amino acid in vegan capsules

Vanilla Vegan Plant Protein — plant protein powder with amino acids added