Glucosamine Chondroitin 1000 mg, 60 Vegan Capsules

What Is Glucosamine + Chondroitin?
Glucosamine + Chondroitin is the classic 2-in-1 joint formula: glucosamine supplies the building blocks for cartilage, and chondroitin helps that cartilage hold water and stay cushioned. Together they are the most-studied joint-support pairing, with decades of trials behind them.

Supplement Facts

Amount Per Serving
Amount
% Daily Value

Glucosamine Chondroitin
1000 mg
*

* Daily Value not established. No split is given between the glucosamine and the chondroitin.
Non-GMO, vegan, gluten free, no additives, no preservatives. Made in the USA.

This is Remedy's value formula — the same 2 core ingredients found in the better-known combinations, without the added MSM. It suits people who want cartilage and water-holding support at a lower price point and prefer a simpler 2-ingredient label.

Glucosamine — supplies cartilage building blocks

Chondroitin — helps cartilage hold water

Quick Facts
1,000 mg per capsule in a vegan shell, glucosamine plus chondroitin, no fillers, made in the USA, 60 capsules per bottle. For the fuller 3-in-1 formula with MSM, see our Glucosamine Chondroitin & MSM.

How Glucosamine and Chondroitin Work
The 2 ingredients complement each other inside the joint. Glucosamine feeds the glycosaminoglycan chains that make up cartilage, while chondroitin helps those chains attract and retain water so cartilage stays spongy under load.

Ingredient
Role in the Joint
Evidence Signal

Glucosamine sulfate
Supplies cartilage building blocks; modulates cartilage enzymes in lab studies
Slowed joint-space narrowing over 3 years[1]Glucosamine Sulfate Slows Knee OA Progression — The Lancet (Reginster 2001) View source

Chondroitin sulfate
Helps cartilage hold water and resist compression
Small, debated symptom benefit in large meta-analyses[2]Chondroitin for Knee or Hip Osteoarthritis Meta-Analysis — Ann Intern Med (Reichenbach 2007) View source

Combined
Cartilage building plus water-holding in 1 capsule
Non-inferior to celecoxib at 6 months in moderate-severe knee OA[3]Glucosamine-Chondroitin Non-Inferior to Celecoxib (MOVES) — Ann Rheum Dis (Hochberg 2016) View source

For the full mechanism, see our explainer on how glucosamine and chondroitin work.
Glucosamine Chondroitin for Knee Osteoarthritis
Knee OA is where this pairing has the most data. The 6-month MOVES trial in 606 adults with moderate-to-severe knee pain found glucosamine plus chondroitin matched celecoxib for pain and stiffness, with fewer side effects[4]Glucosamine-Chondroitin Non-Inferior to Celecoxib (MOVES) — Ann Rheum Dis (Hochberg 2016) View source. Results are best in the moderate-to-severe subgroup; mild cases respond less reliably.
What this pairing tends to deliver in responders:

Pain — comparable to celecoxib at 24 weeks in moderate-severe OA

Stiffness — better morning movement around 8 weeks

Structure — slower joint-space narrowing over 2 to 3 years

For symptom-targeted advice, see our guides to the best supplements for knee pain and joint supplements for arthritis and osteoarthritis.
2-in-1 vs the 3-in-1 with MSM: Which Should You Pick?
The honest difference is MSM. This 2-in-1 covers cartilage building and water-holding; the 3-in-1 adds MSM for extra inflammation and oxidative-stress support. Pick by your goal and budget.

Formula
Best For
Trade-Off

Glucosamine + Chondroitin (this page)
Value cartilage support without MSM
No dedicated inflammation ingredient

Glucosamine + Chondroitin + MSM
The most complete daily joint stack
Slightly higher price

Glucosamine HCL
Single-ingredient, higher concentration
No chondroitin; sulfate has stronger evidence than HCL

Our guide to choosing a glucosamine formula compares all 3 in detail.
Why Choose Remedy's Glucosamine + Chondroitin

What You Get
Why It Matters

2 studied ingredients per capsule
Cartilage building plus water-holding support

1,000 mg per capsule
A meaningful daily amount at a value price

Vegan capsule shell, no fillers
Clean label with 0 artificial binders

60 capsules per bottle
Up to a 2-month supply at 1 capsule daily

Non-GMO, made in the USA
Made under US quality-control standards

Glucosamine Chondroitin Dosage
Take 1 capsule daily with food. Most glucosamine-sulfate trials used 1,500 mg/day, so people with moderate-to-severe OA sometimes split into 2 capsules[5]Safety and Efficacy of Glucosamine and Chondroitin in Humans — Nutrients (Baden 2025) View source. Consistency over 12 weeks matters more than exact timing.

See our full glucosamine dosage guide for ingredient-level detail.
Who Should Choose the 2-in-1
This formula fits people who want the 2 core joint ingredients at a value price and do not need MSM. It is a sensible starting point for early joint care or a step up from glucosamine alone, using the better-studied sulfate form of glucosamine.

Budget-conscious buyers — core ingredients without the MSM premium

Step-up from glucosamine alone — adds chondroitin's water-holding role

Early-stage joint care — best results at the mild-to-moderate stage

If you also want inflammation support, the 3-in-1 with MSM is the more complete next step.
Safety and Side Effects
Glucosamine and chondroitin are well tolerated, with side effects usually mild and dose-related. Contrary to a widespread search worry, neither ingredient directly causes weight gain. The key interaction is with warfarin, where glucosamine has been linked to raised INR[6]Glucosamine-Warfarin Interaction Raises INR — Pharmacotherapy (Knudsen 2008) View source. Talk to a doctor first if you:

Have a shellfish allergy (most glucosamine is shellfish-derived)
Take warfarin or other blood thinners
Are pregnant or breastfeeding
Have surgery planned within 2 weeks

For the complete safety picture, read about glucosamine side effects to know before you take it.
Frequently Asked Questions

How long does glucosamine chondroitin take to work? +
Most users notice changes at 4 to 8 weeks, with meaningful relief at 8 to 12 weeks. The full effect builds over 12 to 24 weeks of daily use. These are not fast-acting painkillers; they work gradually by supplying cartilage building blocks.

What is the difference vs the 3-in-1 with MSM? +
This 2-in-1 has glucosamine and chondroitin only. The 3-in-1 adds MSM for extra inflammation and oxidative-stress support. If you want the most complete daily stack, the 3-in-1 is the better fit; this version is the value option at a lower price.

Is glucosamine chondroitin safe long-term? +
Yes for most healthy adults. These 2 ingredients have been studied for up to 36 months without major safety concerns, and side effects appear in under 5% of users. People with shellfish allergy, diabetes, or on warfarin should consult a doctor first.

Does glucosamine chondroitin cause weight gain? +
No. Neither glucosamine nor chondroitin has been shown to cause weight gain in trials lasting up to 3 years. The myth comes from insulin-resistance fears that a 90-day HbA1c study did not confirm. If your weight shifts, look to diet or activity first, not this 1-a-day formula.

Will it help my knees? +
It helps some people more than others. In the 606-patient MOVES trial, the combination matched celecoxib for moderate-to-severe knee OA over 6 months. About 50 to 60% of users notice benefit; 12 weeks of consistent use gives the best chance.

How many capsules should I take? +
Take 1 capsule daily with food for maintenance. For moderate-to-severe OA, 2 capsules daily moves you toward the 1,500 mg glucosamine range used in most trials. Stay consistent for at least 12 weeks before judging the effect.

Is it safe with a shellfish allergy? +
About 80% of glucosamine comes from shellfish shells, a concern if you are allergic. The molecule itself lacks the allergen protein, but cross-contamination is possible. If you have a shellfish allergy, choose a clearly labeled vegetarian glucosamine and check the allergen disclosure first.

Can I take it with ibuprofen? +
Yes for short-term use. They work on different pathways, so many people use this supplement daily plus occasional ibuprofen for flares. Over 6 months, the supplement is gentler than continuous NSAIDs on the gut and heart. Ask your doctor about chronic pain plans.

Should I stop before surgery? +
Yes. Stop at least 2 weeks before any planned surgery because glucosamine has mild blood-thinning potential. Tell your surgeon every supplement you take, and resume only once cleared, usually 1 to 2 weeks after the procedure.

Does it affect blood sugar? +
Usually not. A 90-day trial in well-controlled type 2 diabetes found no rise in HbA1c. If you have diabetes, monitor your blood sugar for the first 2 weeks of daily use and talk to your prescriber about any adjustment.

Should I take it with food? +
Yes, with a meal. Food can cut the chance of mild GI upset by roughly half. The supplement does not need dietary fat for absorption, but a small meal buffers the stomach. Many people take it with breakfast as the 1 daily habit they will not forget.

Is chondroitin worth adding to glucosamine? +
It depends on your goal. Chondroitin's solo symptom benefit is small in large meta-analyses, but it adds water-holding support glucosamine alone lacks. In the 606-patient MOVES trial, the pairing matched a prescription NSAID, so many people prefer the 2-ingredient formula over glucosamine by itself.

Can I take it with warfarin? +
Only with medical supervision. Glucosamine has been linked to raised INR in warfarin users in case reports. If you take warfarin, do not start without your prescriber's approval and more frequent INR monitoring, at least for the first 2 to 4 weeks.

How does this compare to glucosamine HCL? +
This 2-in-1 uses the sulfate form plus chondroitin. Glucosamine HCL is a single ingredient with a higher glucosamine concentration but no chondroitin. Importantly, glucosamine sulfate has the stronger trial record, so concentration alone is not the deciding factor.

Is this glucosamine vegan? +
No. The capsule shell is vegan, made from plant cellulose rather than gelatin, but the glucosamine itself is shellfish-derived, as most glucosamine is. Anyone with a shellfish allergy should avoid it. Only the shell of the 60 capsules is a plant material.

You May Also Like

Glucosamine + Chondroitin + MSM — the fuller 3-in-1 with added MSM for inflammation support

Glucosamine HCL — single-ingredient, higher-concentration glucosamine option